Tag: hydrophilic matrix

Formulation and Study of Some Controlled Release Tablets With Pentoxifylline Based on Hydroxypropylcellulose Matrix Obtained by Wet Granulation Method With Peg 6000

In this work three formulations of modified release tablets containing pentoxifylline 400 mg/tablet were obtained. Hydroxypropylcellulose (HPC) in di®erent ratios was used as hydrophilic matrix agent. The pentoxifylline inclusion in the matrix has been carried out by water granulation, using PEG 6000 as binder. Tablets were obtained with a single